ACADEMIC/EMPLOYMENT DETAILS

ACADEMIC ACHIEVEMENTS AWARDS AND FELLOWSHIPS

? Received DBT-MSc. Scholarship for two years of my MSc. Programme

?Gold Medallist MSc. Biotechnology, Kashmir University, J&K, 2008

? Qualified DBT-JRF Examination in the years 2008 and 2009

?Qualified CSIR-NET-JRF, Life Sciences, Dec. 2008

?Qualified Ph.D. Life Sciences, Jawaharlal Nehru University, New Delhi, 2008

?Received Registration Waiver Grant from the 4^th FEBS special meeting ABC2012 organizers to attend and present a poster in the ABC Meeting held at Innsbruck, Austria, from 03 Mar 2012 to 09 Mar 2012.

• Received CSIR-Foreign Travel Grant to attend and present a poster at the ABC Meeting held at Innsbruck, Austria, from 03 Mar 2012 to 09 Mar 2012

?Received International Travel Support (ITS) from DST-India to attend and present a poster in the 5^th FEBS Advanced Lecture Course Human Fungal Pathogens held at Nice, France, during May 25-31, 2013

? My work was selected for oral presentation at the 12^th ASM Conference on Candida and Candidiasis held in New Orleans, Louisiana, USA, March 26 – 30, 2014, and I received the following fellowships/assistance to attend the same:

     • Received Foreign Travel Grant from ICMR-India to deliver an oral talk and present a poster at 12^th ASM Conference on Candida and Candidiasis held in New Orleans, Louisiana, USA, March 26 – 30, 2014

     • Received JNU Corpus Fund from Jawaharlal Nehru University (JNU), New Delhi, for participation in 12^th ASM Conference on Candida and Candidiasis held in New Orleans, Louisiana, USA, March 26 – 30, 2014

• Received partial assistance from the Indian National Science Academy (INSA), New Delhi, for participation in the 12^th ASM Conference on Candida and Candidiasis held in New Orleans, Louisiana, USA, March 26 – 30, 2014

?Received ASM travel expenses for young scientists to deliver an oral talk and present a poster at the 12th ASM Conference on Candida and Candidiasis held in New Orleans, Louisiana, USA, March 26 – 30, 2014

? Was appointed as Senior Research Fellow from July 2014 to January 2015 in a DBT-funded project “Mutational analysis of multidrug ABC transporter to dissect the mechanism of drug efflux” at the School of Life Sciences, Jawaharlal Nehru University, New Delhi

?My work was selected for oral presentation at “the 9^th ISHAM”, Australia, May 4–8, 2015, and I received a CSIR-Foreign Travel Grant to attend the same.

? Was awarded CSIR Research Associateship vide file number No.212232/2K14/1, June 2015.

? Was appointed as Young Ambassador to India by the American Society for Microbiology for the year 2020-2022

?Received CSIR-Senior Research Associate Award (CSIR-Scientists Pool Scheme) vide File No. B-12797 in Life Sciences, June 2021

?Received Bill & Melinda Gates Foundation Travel Award to attend World Microbe Forum, June 20-24, 2021, a joint digital event between ASM Microbe 2021 and FEMS Congress 2021.

?Received DBT travel grant to attend the ASM Microbe 2022 meeting as an ASM Young Ambassador to India held in Washington D.C, USA from June 9-13, 2022

?Was awarded CSIR-Foreign Travel Grant to attend the ASM Microbe 2022 meeting as an ASM Young Ambassador to India held at Washington D.C, USA from June 9-13, 2022

?Was awarded European Molecular Biology Organization (EMBO) Travel and registration fee waiver grants to attend the EMBO Workshop “Membrane transporters as essential elements of cellular function and homeostasis” 23 – 27 August 2022 at Chania, Greece

?Was awarded the India Bioscience Outreach grant (4^th IOG Grant) as Lead applicant by India Bioscience for the year 2023-24.

?Secured “Second Position” in Oral Presentation competition held during “India Bioscience- Regional Young Investigators Meeting” held at the University of Kashmir, Srinagar, J&K from 19-21 Sep. 2023.

RESEARCH PROJECTS:

OUTREACH GRANTS:

PUBLICATIONS:

All the publications are Joint authored publications, refereed and indexed, and are from international publishers appearing in UGC-CARE List Group II indexed inglobally recognized databases like Scopus and Web of Science

1. Novel role of a family of major facilitator transporters in biofilm development and virulence of Candida albicans.  Shah AH, et al. Biochem. J. (2014) 460: 223–235. (IF-4.3) ISSN No. 0264-6021/1470-8728
   1. Mutational analysis of intracellular loops identify cross talk with nucleotide binding domains of the yeast ABC transporter Cdr1p.  Shah AH, et al. Sci Rep. (2015) 5:11211. (IF-3.9) ISSN No.2045-2322
   2. ABC transporter Cdr1p harbors charged residues in the intracellular loop and nucleotide-binding domain critical for protein trafficking and drug resistance. Shah AH, et al. FEMS Yeast Res (2015) 15, fov036. (IF-3.2) ISSN No.1567-1356/1567-1364
   3. Quinidine drug resistance transporter knockout Candida cells modulate glucose transporter expression and accumulate metabolites leading to enhanced azole drug resistance. Qadri H, Shah AH*, et. al. Fungal Genet Biol. (2022);161:103713 (IF-2.4) ISSN No.1087-1845/1096-0937
   4. Glucose metabolic reprogramming and modulation in glycerol biosynthesis regulates drug resistance in clinical isolates of Candida. Padder SA, Padder RA, Ramzan A, Bashir G, Tahir I, Rehman RU, Shah AH*. J Appl Microbiol. (2023);134:lxad091 doi: 10.1093/jambio/lxad091 (IF-3.2) ISSN No.1364-5072/1365-2672
   5. Physicochemical and anti-fungal studies of pharmaceutical cocrystal/salt of fluconazole. Ahangar AA, Qadri H, Malik AA, Mir MA, Shah AH* and Dar AA. ACS Mol. Pharmaceutics. (2023) doi: 10.1021/acs.molpharmaceut.3c00087 (IF:4.5) ISSN No.1543-8384/1543-8392
   6. Dual antifungal and antiproliferative activities of a novel protein fraction from a medicinally important herb Trillium govanianum Wall. ex. D. Don. Wani, S.S., Qadri, H., Shah, A.H* et al. Appl Biochem Biotechnol (2023). https://doi.org/10.1007/s12010 (IF 3.3) ISSN No.0273-2289/1559-0291
   7. MFS transporters of Candida species and their role in clinical drug resistance. Redhu AK, Shah AH,and Prasad R. FEMS Yeast Res. (2016) 16. pii: fow043 (IF-2.4) ISSN No.1567-1356/1567-1364
   8. Novel strategies to combat the emerging drug resistance in human pathogenic microbes. Qadri H, Shah AH*, Mir MA. Current Drug Targets (2021) 22, 1-13 (IF-2.5) ISSN No.1389-4501/1873-5592
   9. The clinical praxis of bacteriocins as natural anti-microbial therapeutics. Nisar S, Shah AH*, Nazir R. Arch Microbiol. (2024); 206:451. (IF-2.3). ISSN No.0302-8933/1432-072X

1. 1.      In vitro effect of malachite green on Candida albicans involves multiple pathways and transcriptional regulators UPC2 and STP2. Dhamgaye S, Devaux F, Manoharlal R, Vandeputte P, Shah AH, et al. Antimicrob Agents Chemother. (2012) 56:495-506.  (IF-4.9) ISSN No.0066-4804/1098-6596
2. Alanine scanning of all cysteines and construction of a functional cysteine-less Cdr1p, a multidrug ABC transporter of Candida albicans. Prasad R, Shah AH, et al. Biochem Biophys Res Commun. (2012) 417:508–513.(IF-3.1) ISSN No.0006-291X/1090-2104
3. Newly identified motifs in Candida albicans Cdr1 protein NBDs are PDR subfamily-specific and functionally asymmetric. Rawal MK, Banerjee A, Shah AH, et al. Sci Rep (2016) 6: 27132. (IF-3.9) ISSN No.2045-2322
4. W1038 near D-loop of NBD2 is a focal point for inter-domain communication in multidrug transporter Cdr1 of Candida albicans. Banerjee A, Shah AH, et al. Biochem Biophys Acta-Biomembranes (2018) 1860:965-972. (IF-3.4) ISSN No.0005-2736/1879-2642
5. 5.      Identification of genome-wide alternative splicing events in sequential, isogenic clinical isolates of Candida albicans reveals a novel mechanism of drug resistance and tolerance to cellular stresses. Muzafar S, Sharma RD, Shah AH, et. al. mSphere (2020);5:e00608-20 (IF-3.1) ISSN No.2379-5042
6. In vitro potent anticancer, antifungal, and antioxidant efficacy of walnut (Juglans Regia L.) Genotypes. T Ara, S Shafi, M Ghazwani, JI Mir, AH Shah, RA Qadri, AR Hakami Agronomy. (2023)13, 1232. (IF-3.4) ISSN No.2073-4395
7. Natural products and their semi-synthetic derivatives against antimicrobial-resistant human pathogenic bacteria and fungi. Qadri H., Shah AH, Andrabi S.M., Alshehri B., Almilaibary A., Mir M.A. Saudi J Biol Sci. (2022);29:103376. (IF-4.4) ISSN No.1319-562X/2213-7106
8. Crystal engineering considerations for pharmaceutical co-crystals. Khazir S, Shah AH, Parambil JV and Dar AA. CrystEngComm, (2025);27:7418-7442 (IF-2.6)  ISSN No.1466-8033
9. Molecular basis of substrate polyspecificity of the Candida albicans Mdr1p multidrug/h+ antiporter. Redhu AK, Banerjee A, Shah AH, et al. J Mol Biol. (2018) 430:682-694. (IF-4.5) ISSN No.0022-283/1089-8638

1. Pharmaceutical Salts of Azole Anti-fungal Drugs: Physicochemical Behaviour and Activity Studies. Qadri H, Malik A.A, Ahangar A.A, Mir M.A, Dar A.A and Shah A.H*. RSC Pharmaceutics, (2024) 1,705-715 (IF-N.A)  ISSN No.2976-8713

1. β-Nitrostyrene derivatives as broad range potential antifungal agents targeting fungal cell wall. Ramzan A., Padder S.A., Masoodi K.Z., Shafi S., Tahir I., Rehman R., Prasad R., Shah AH*. Eur J Med Chem. (2022);240:114609 (IF-6.7) ISSN No.0223-5234/1768-3254
2. Quorum sensing: A less known mode of communication among fungi. Padder SA, Prasad R, Shah AH*. Microbiol Res. (2018) 210:51-58 (IF-6.7) ISSN No.0944-5013/1618-0623
3. Glucose-The X-factor for the survival of human fungal pathogens and disease progression in the host. Qadri H, Qureshi MF, Mir MA, Shah AH* Microbio. Res (2021) 247, 126725. (IF-6.7) ISSN No.0944-5013/1618-0623
4. Metabolic flexibility and extensive adaptability governing multiple drug resistance and enhanced virulence in Candida albicans.  Padder SA, Ramzan A, Tahir I, R Reiaz ul, Shah AH*. Crit Rev Microbiol. (2022);48:1-20 (IF-6.5) ISSN No.1040-841X/1549-7828

1. Resistance to antifungal therapies. Prasad R, Banerjee A, Shah AH. Essays in Biochemistry (2017) 61:157-166 (IF-6.4) ISSN No.0071-1365/1744-1358

1. Mechanism of drug resistance in fungi and their significance in biofilms. Prasad R, Shah AH, Dhamgaye S. In: Antibiofilm Agents: From Diagnosis to Treatment and Prevention, Part I (2014) 8: 45-65. Springer Berlin Heidelberg 2014. Ed. K.P. Rumbaugh and I. Ahmad. ISBN No. 978-3-642-53832-2
2. Antifungals: mechanism of action and drug resistance. Prasad R, Shah AH, Rawal MK. In: Membrane Transport in Yeast, Advances in Experimental Medicine and Biology, (2016) 892: 327-349. Springer International Publishing Switzerland. Ed. José Ramos, Hana Sychrova and Maik Kschischo (IF 3.65) ISBN No. 978-3-319-25302-2/978-3-319-25304-6
3. Candida efflux ATPases and antiporters in clinical drug resistance. Prasad R, Rawal MK, Shah AH. In: Membrane Transport in Yeast, Advances in Experimental Medicine and Biology, (2016) 892: 351-376. Springer International Publishing Switzerland. Ed. José Ramos, Hana Sychrova and Maik Kschischo (IF 3.65) ISBN No. 978-3-319-25302-2/978-3-319-25304-6
4. Tools and Techniques to Study Multidrug Transporters of Yeasts. Shah AH, et al. In: Modern Tools and Techniques to Understand Microbes. (2017) doi: 10.1007/978-3-319-49197-4_12 pp183-207. Springer International Publishing AG. Ed. A. Varma, A.K. Sharma. ISBN No. 978-3-319-49195-0
5. Combating human fungal infections: need for new antifungal drugs and therapies. Mir, M. A., Qadri, H., Aisha, S., & Shah, AH. In: Human Pathogenic Microbes: Diseases and Concerns, (2022) doi:10.1016/B978-0-323-96127-1.00010-3 pp103-128. Elsevier Science Publishers USA. Ed. MA Mir. ISBN No. 1032395426X,9780323954266
6. Role of immunogenetics polymorphisms in infectious diseases. Qadri, H., Shah, AH, & Mir, M. A. (2022). In: A Molecular Approach to Immunogenetics (pp. 169-191). Elsevier Science Publishers USA. Ed. MA Mir. ISBN No. ISBN: 978-0-323-90053-9
7. Antifungal Therapies and Drug Resistance. Qadri H., Mir M. A., Shah A.H. In: Human Fungal Diseases (2024). DOI: 10.1201/9781032642864-10. CRC Press; Taylor and Francis group. Ed. Hameed S. ISBN No.  9781032642864

CONFERENCES ATTENDED

• § Participated in “International Symposium on Genomic Instability and Cancer”, organized jointly by the DBT, Kashmir University, Department of Medical Oncology, SKIMS Srinagar, and The Ohio State University, USA, held at Srinagar, Kashmir, India, from July 22-26, 2007.
• § Participated in international conference, “28^th Small Meeting on Yeast Transporters and Energetics (SMYTE)”, New Delhi, India, 2010.
• § Presented a poster at “The Indian Proteomics conference” held at Jawaharlal Nehru University, New Delhi, from 3rd to 5th April 2011.
• § Presented a poster at the 81^st Society of Biological Chemists’ conference organized by SBCI India, Nov. 2011.
• § Presented a poster at the 4^th FEBS Special meeting on ATP Binding Cassette (ABC) proteins: From Multidrug Resistance to Genetic Diseases, held at Innsbruck, Austria, from 3rd to 9th March 2012.
• § Presented a poster in “The 5^th FEBS HFP: Molecular Mechanisms of Host-Pathogen Interactions and Virulence”, held at La Colle sur Loup, Nice, France from May 25-31, 2013.
• § Presented a poster in an international meeting “20 years of CDR1 Research” organized by the School of Life Sciences, Jawaharlal Nehru University, held at Hotel Crowne Plaza, Rohini, New Delhi from 4-7 Jan 2014
• § Delivered an oral talk in Biosparks 2014 meeting held in School of Life Sciences, JNU, New Delhi, March 21st – 22nd, 2014
• § Delivered an oral talk and presented a poster in the 12^th ASM Conference on Candida and Candidiasis, organised by ASM, held in New Orleans, Louisiana, USA, March 26 – 30, 2014
• § Participated in a 3-day lecture programme on Mathematical Modelling of Biological Systems organised by the Department of Mathematics, University of Kashmir, Srinagar, India, April 2-4, 2015
• § Delivered an oral talk in the “9^th Congress of ISHAM, held in Melbourne, Australia, May 4–8, 2015.
• § Presented a poster in “9^th Young Investigators Meeting (YIM-2017)” held in Goa, India, March 6-10, 2017
• § Presented a poster in “35^th SMYTE meeting”, held at Amity University, Gurgaon, India, Sep 17-21, 2017
• § Participated in “10th Conference on Yeast Biology” held at JNU, New Delhi, India, February 8-11, 2018
• § Presented a poster in the “1^st DBT/DST Joint Conclave meeting” held at Jaipur, India, June 8-10, 2018
• § Participated in First Annual Research Meet: Recent Trends in Cell & Molecular Biology held at University of Kashmir, Jammu and Kashmir, India, March 19-20, 2019.
• § Delivered an oral talk in the “60^th Annual Conference of AMI” held at CUH, India, November 15-18, 2019.
• § Presented a poster in the “World Microbiome Forum meeting 2021” held online worldwide and organized jointly by ASM and FEMS from June 20-24, 2021.
• § Participated in the “ASM Microbe 2022” meeting as an ASM Young Ambassador to India held at Washington, D.C, USA from June 9-13, 2022.
• § Presented a poster in the EMBO Workshop “Membrane transporters as essential elements of cellular function and homeostasis held in Chania, Greece, from August 23 – 27, 2022.
• § Delivered an oral talk during “IndiaBioscience-Regional Young Investigators Meeting” held at the University of Kashmir, Srinagar, J&K from 19-21, Sep. 2023.

GROUP (PH.D. STUDENTS AWARDED/ ONGOING)

• Dr. Sajad Ahmad Padder (Ph. D. awarded)
• Dr. Asiya Ramzan (Ph. D. Awarded)
• Dr. Hafsa (Ph. D. Awarded)
• Dr. Asif A Malik (Ph.D. Awarded)
• Ms. Safura Nisar (Ph.D. Ongoing)
• Dr. Sheikh Owais Mohd. (Project SRF/ongoing)
• Ms. Summaya Khazir (Project JRF/ongoing)

MEMBERSHIPS IN THE SCIENTIFIC SOCIETIES

• · The lifetime member of the Society of Biological Chemists, India (SBCI). (No. 2951)
• · Post-doctoral member of the American Society for Microbiology (ASM), USA. (No. 41786450)
• · Young active member of the International Society for Human and Animal Mycology (ISHAM). (No. MM5542)
• · Lifetime member of the Association of Microbiologists of India (No. 4839-2019)
• · Lifetime member of Microbiologists Society, India, (No. MS/LM/655)
• · Annual Member of Applied Microbiology International (No. 457301)

MASTERS PROJECTS GUIDED

Have guided the following students for their MSc. dissertation programme

? “Site-directed mutagenesis of Cdr1p an ABC transporter of Candida albicans” by Vikash Kumar Gupta

? “Mutational analysis of ICL2 of Cdr1p, an ABC multidrug transporter of Candida albicans” by Rashmi Pathak

? “Characterization of some mutants of ICL3 in Cdr1p, an ABC multidrug transporter of Candida albicans” by Shivangee Bansal

? “Alanine scanning mutagenesis of amino acid residues of Cdr1p, an ABC multidrug transporter of Candida albicans” by Mahima Jaiswal

? “Role of interdomain communication in the transport function/localization of multidrug ABC transporter Cdr1p of Candida albicans” by Preeti

? “Effect of novel compounds on the growth of drug-resistant human pathogenic fungi” by Muteeba Mushtaq Dedmari, Subrina Gulzar, and Gousia Amin

? “Activity of some novel Beta-Nitostyrenes against the growth of human pathogenic fungi” by Arfa, Ulfat Rashid, and Insha Hasaan

? “Generation of reactive oxygen species and its scavenging in living systems” by Mehrajul Nisa, Shikha Pandita, Shaista Manzoor, and Farhat Sharief

? “Candida and pathogenesis in human hosts, a systematic analysis” by Saleeka Yaseen, Ulfat Jan, and Mohammad Usman

? “Sequence analysis of TAC1 binding element in drug resistance genes across different Candida species” by Summaya Habib, Afreen Mushtaq, Seerat Rayees

? “Evaluation of the antimicrobial activity of plant extracts and animal proteins against microbial pathogens” by Aamir Nazir Malik, Arizoo Maqbool, Sayeema Jan, Iqra Farooq

? “Exploring the combinatorial activity of plant extracts/oils and azole drugs against the emerging human fungal pathogen Candida auris” by Humaira Tabasum, Suhail Ahmad Najar, Ifshana Mohi Ud Din, Ifra Bilal

“Isolation and identification of different microorganisms from various soil samples” by Naina Yousuf     , Mymoona Jan, Snober Gulzar, Azana Ayoub, Ishfaq Ahmad Magray

SCIENCE AND RESEARCH OUTREACH ACTIVITIES

• Delivered an invited talk on Structural and Functional Analysis of multidrug resistance proteins of pathogenic Candida at Amity University, Haryana, on 30-03-2017
• Was appointed as an ASM Young Ambassador to India by the American Society for Microbiology for three years from 2020 to 2023
• Was inducted into the core member leadership team of the JK Scientists, which is a registered non-profit organization working for science and research outreach activities in the UT of J&K (since 17-10-2020)
• Organised an ASM awareness lecture on novel Coronavirus (COVID-19) on 14-03-2020 at the University of Kashmir, Srinagar-J&K
• Organised a Seminar on Good Laboratory Practices at SKIMS, Soura, Srinagar, J&K on 26-10-2020 (Also acted as Resource Person)
• Organised a Workshop on Scientific Writing and Publishing on 07-04-2021 via online mode
• Participated in JKScientists Summer Outreach Programme at Degree College Ganderbal, J&K on 21-05-22 (Acted as one of the Resource Persons)
• Delivered a lecture on "Basic techniques in microbiology & molecular biology" in an FDP at Dept. of Bioresources, University of Kashmir (20-26 September 2022)
• Gave a "Practical demonstration related to molecular and microbiological techniques" to the participants in an FDP at the Department of Bioresources, University of Kashmir (20-26 September 2022)
• Organised a Lecture Session on the Conservation of Microbial Diversity and AMR on 23-11-2022 at DAV College, Chandigarh (Also acted as one of the Resource Persons)
• Organised a Workshop on Water Quality Testing and Innovation Training on 10-12-2022 at the Govt. Degree College Ganderbal, J&K (Also acted as Resource Person)
• Delivered an invited lecture in Ten days training programme on Microbiological Methods, 7th-17th March 2023, at SKUAST, Kashmir
• Participated in JKScientists Outreach Program at University of Kashmir Srinagar J&K- on 18-07-2023 (Acted as one of  the Resource Persons)
• Participated in JKScientists Outreach Program held at SP College & Women’s College, M.A Road Srinagar J&K- on 2-08-2023 (Acted as a Resource Person)
• Was appointed as Coordinator (J&K) for Microbiologists Society, India for the year 2022-23.
• Was appointed as Vice-President of the J&K state for the Microbiologists Society, India, for the year 2023-24.
• Organised a one-day workshop entitled “Microbes through Foldscope for beginners” at the Government. Degree college Pulwama on 18-09-23, J&K-India, in association with IndiaBioscience, University of Kashmir, International Microorganisms Day, and Microbiologists Society-India. 
• Organised IndiaBioscience “Young Aspirants Meet-24” in association with JKScientists on 25^th July 2024 as Lead Organiser at EMMRC auditorium, University of Kashmir, Srinagar, J&K.

REFERENCES

• Prof. Rajendra Prasad

Amity University Haryana, Gurgaon, India; Email: rprasad@ggn.amity.edu; rp47jnu@gmail.com

• Prof. Mohd. Ayub Qadri

Dean: School of Health Sciences, IUST, Kashmir; Email: ayub.qadri@iust.ac.in

• Prof. Inayatullah Tahir

Dept. of Botany, University of Kashmir, Srinagar; Email: inayatullahtahir@gmail.com

• Prof. Shyamal K. Goswami

School of Life Sciences, Jawaharlal Nehru University; Email: skgoswami@mail.jnu.ac.in