Assistant Professor

Dr Manzoor was Born at Trehgam Kupwara Kashmir. He completed his M Sc in Life Sciences (Zoology). He qualified JRF-NET and joined Ph. D in Immunology at IMTECH-CSIR-JNU. In 2009 he topped the Asstt. Prof List by JKPSC & in 2011 he was nominated as Nodal Officer for Kashmir University Satellite Campus at Kupwara. He got selected as Asstt. Prof in Deptt of Bioresources, KU in 2012 . He worked in SATCAS Stroke Research Chair with Prof Raid at MU KSA from 2013-2015. He has wrote seven international books with reputed international Publishers like Elsivier USA, Nova Science Publishers USA and Academic Press USA. He has published many research articles in the Journals of internal repute which include, Cellular Oncology, Breast Cancer, Current drug targets,  Current Pharmaceutical Biotechnology, Future Oncology, Microbiological Research, Journal of Biomedical Nanotechnology, Current Cancer Drug Targets, Plos One, Expert Opinion in Therapeutic Targets, Frontiers in Neurosciences, Stroke, Advances in Neuroimmune Biology etc. He has presented research papers and delivered talks in various international Scientific conferences in the countries like USA, UK, China, Bahrain, UAE, Scotland, Kuwait & Sri lanka. His Research interests include, Immunobiology of Cancer, Immunology of Tubersulosis and Immunology of Stroke. He is member of many scientific organizations and societies like American Association of Cancer Research, Fellow of Royal British Society, International Immunology Association, Indian Cancer Society, Indian Immunology Society, Indian National Science Association, IMMUNOCON etc. Dr Manzoor was awarded Teachers Associate Research Excellence Fellowship (TARE) by DST Govt of India. He has been awarded Summer Research Fellowship Programme (SRFP-2019) by Indian Academy of Sciences and National Science Academy. He was awarded a research project on combination therapy in breast cancer by Jammu Kashmir Science Technology and Innovation council, Govt of J&K. Dr Manzoor has developed Massive Open Online Course (MOOCs) in Immunology course and Endocrinology course for UG students sanctioned by UGC-Consortium for Educational Communication (CEC) SWAYAM Ministry of HRD Govt of India. He has research and teaching experience of 15 years. He currently teaches Cancer Biology, and Immunology at the Department of Bioresources, School of Biological Sciences, University of Kashmir. He is presently heading the Department of Bioresources, University of Kashmir.

Faculty Details

  • Citations 650
  • HIndex 16
  • i10 Index 20
  • Mobile 9622901319
  • Email drmanzoor@kashmiruniversity.ac.in
  • Administrative position Held Coordinator Department of Bioresources School of Biological Sciences
  • Resume View



Research Papers Published

  • "Inflammatory Mechanisms as Potential Therapeutic Targets in Stroke" Advances in Neuroimmune Biology, 5(1): 199 -216 {ISSN: 1878-9498}
  • "Effect of Supine Versus Semi-Fowler’s Position on Hemodynamic stability of patients with Head injury" World Journal of Pharmaceutical Research, 4(4): 121 -130 {ISSN: 2277-7105}
  • "123I-FP-CIT SPECT imaging in early diagnosis of dementia in patients with and without a vascular component" Frontiers in System Neurosciences, 9(99): 1 -11 {ISSN: 1662-5137}
  • "Immunomodulation of Inflammatory Markers in Activated Macrophages by Leaf Extracts of Gingko Biloba" Advances in Neuroimmune Biology, 5(5): 127 -139 {ISSN: 1878-9498}
  • "TNF Receptor Modulation by Gentiana Extracts Acts as Neuroprotective Mechanism in Stroke by Enhancing Cellular Survival." Stroke, 45(12): e259 -298 {ISSN: 1524-4628}
  • "Immunomodulation of Inflammatory Markers in Activated Macrophages by Leaf Extracts of Gingko Biloba" Advances in Neuroimmune Biology, 6(1): 9 -17 {ISSN: 1878-9498}
  • "BAD a Proapoptotic Protein Escapes ERK RSK Phosphorylation in Deguelin and siRNA Treated HeLa Cells" Plos One, 11(1): Pub Med ID. PMC4706341 {ISSN: 19326203}
  • "Impact of co-signaling on the survival of intracellular pathogens in macrophages" International Journal of Advance Research in Science and Engineering, 7(4): 3166 -3183 {ISSN: 2319-8354}
  • "Double-Crosser of the Immune System: Macrophages in tumor progression and metastasis" Current Immunological Reviews, 15(2): DOI No. 10.2174/1573395515666190611122 {ISSN: 1875-631X}
  • "Recent advances in metabolites from medicinal plants in cancer prevention and treatment" Current Immunological, 15(2): DOI No. 10.2174/1573395515666191102094 {ISSN: 1875-631X}
  • "Nanobodies: the magic bullets in therapeutics, drug delivery and diagnostics" Human Antibodies, 21(1): DOI No. 10.3233/HAB-190390 {ISSN: 1875-869X}
  • "Recent Advances in Chemotherapeutic Implications of Deguelin, A Plant Derived Retinoid" The Natural Products Journal, 11(2): DOI No. 10.2174/2210315510666200128125 {ISSN: 2210-3163}
  • "Targeting Different Pathways Using Novel Combination Therapy in Triple Negative Breast Cancer" Current Cancer Drug Targets, 20(8): DOI No. 10.2174/1570163817666200518081 {ISSN: 1873-5576}
  • "Development of New Therapeutics to Meet the Current Challenge of Drug Resistant Tuberculosis" Current Pharmaceutical Biotechnology, 22(4): DOI No. 10.2174/1389201021666200628021 {ISSN: 1873-4316}
  • "Rising trends of Cancers in Kashmir valley: Distribution Pattern, Incidence and Causes" Journal of Oncology Research and Treatment, 5(2): 150 -163
  • "Novel Strategies to Combat the Emerging Drug Resistance in Human Pathogenic Microbes" Current Drug Targets, 22(17): DOI No. 10.2174/1389450121666201228123 {ISSN: 1873-5592}
  • "Tumor microenvironment promotes breast cancer chemoresistance" Cancer Chemotherapy and Pharmacology, 87(2): DOI No. 10.1007/s00280-020-04222-w {ISSN: 1432-0843}
  • "Glucose - The X factor for the survival of human fungal pathogens and disease progression in the host" Microbial Research, 247(6): DOI No. 10.1016/j.micres.2021.126725 {ISSN: 2036-7481}
  • "Prognostic significance and targeting tumor-associated macrophages in cancer: new insights and future perspectives" Breast Cancer, 28(3): DOI No. 10.1007/s12282-021-01231-2 {ISSN: 1880-4233}
  • "Recent Advances in Chemotherapeutic Implications of Deguelin: A Plant-Derived Retinoid" The Natural Products Journal, 11(2): DOI No. 10.2174/2210315510666200128125 {ISSN: 2210-3163}
  • "Comparative Study on Phytochemical Profile and Antioxidant Activity of an Epiphyte, Viscum album L. (White Berry Mistletoe), Derived from Different Host Trees" Plants, 10(6): DOI No. 10.3390/plants10061191 {ISSN: 2223-7747} Impact Factor= 3.935
  • "Glucose - The X factor for the survival of human fungal pathogens and disease progression in the host" Microbiological Research, 247(6): DOI No. 10.1016/j.micres.2021.126725 {ISSN: 0944-5013} Impact Factor= 5.415
  • "Prognostic significance and targeting tumor-associated macrophages in cancer: new insights and future perspectives" Breast Cancer, 28(5): DOI No. 10.1007/s12282-021-01231-2 {ISSN: 1880-4233} Impact Factor= 4.234
  • "Development of New Therapeutics to Meet the Current Challenge of Drug Resistant Tuberculosis" Current Pharmaceutical Biotechnology, 22(4): DOI No. 10.2174/1389201021666200628021 {ISSN: 1873-4316} Impact Factor= 2.987
  • "Tumor microenvironment promotes breast cancer chemoresistance" Cancer Chemotherapy and Pharmacology, 87(2): DOI No. 10.1007/s00280-020-04222-w {ISSN: 1432-0843} Impact Factor= 3.333
  • "The tumor microenvironment as driver of stemness and therapeutic resistance in breast cancer: New challenges and therapeutic opportunities" Cellular Oncology, 44(5): DOI No. 10.1007/s13402-021-00634-9 {ISSN: 22113428} Impact Factor= 6.730
  • "An insight into the cancer stem cell survival pathways involved in chemoresistance in triple-negative breast cancer" Future Oncology, 17(31): DOI No. 10.2217/fon-2021-0172 {ISSN: 1744-8301} Impact Factor= 3.404
  • "Strategies employed to evade the host immune response and the mechanism of drug resistance in Mycobacterium tuberculosis: In search of finding new targets" Current Pharmaceutical Biotechnology, 22(17): DOI No. 10.2174/1389201023666211222164 {ISSN: 1873-4316} Impact Factor= 2.987
  • "Nano-Drug Delivery Systems: Possible End to the Rising Threats of Tuberculosis" Journal of Biomedical Nanotechnology, 17(12): DOI No. 10.1166/jbn.2021.3201 {ISSN: 1550-7041} Impact Factor= 4.483
  • "In vitro and in silico evaluation of antimicrobial properties of Delphinium cashmerianum L., a medicinal herb growing in Kashmir, India" Journal of Ethnopharmacology, 291(6): DOI No. 10.1016/j.jep.2022.115046 {ISSN: 0378-8741} Impact Factor= 4.360
  • "Expression pattern and prognostic significance of baculoviral inhibitor of apoptosis repeat-containing 5 (BIRC5) in breast cancer: A comprehensive analysis" Advances in Cancer Biology - Metastasis, 4(7): DOI No. 10.1016/j.adcanc.2022.100037 {ISSN: 2667-3940}
  • "Chemokines in triple-negative breast cancer heterogeneity: New challenges for clinical implications" Seminars in Cancer Biology, 80(3): DOI No. 10.1016/j.semcancer.2022.03.00 {ISSN: 1044-579X} Impact Factor= 15.707
  • "Metformin treatment ameliorates endocrine-metabolic disturbances in letrozole-induced PCOS mice model by modulating adiponectin status" Obesity Medicine, 31(5): DOI No. 10.1016/j.obmed.2022.100392 {ISSN: 2451-8476} Impact Factor= 1.5
  • "Chemokines in triple- negative breast cancer heterogeneity: New challenges for clinical implications" Seminars in Cancer Biology, 84(3): DOI No. 1 {ISSN: 1044-579X} Impact Factor= 17.012
  • "Adapalene and doxorubicin synergistically promote apoptosis of TNBC Cells by hyperactivation of the ERK1/2 pathway through ROS induction" Frontiers in Oncology, 12(6): DOI No. 10.338 {ISSN: 2234-943X} Impact Factor= 6.244
  • "Adapalene inhibits the growth of triple-negative breast cancer cells by S-phase arrest and potentiates the antitumor efficacy of GDC- 0941" Frontiers in Pharmacology, 13(7): DOI No. 10.3389/ {ISSN: 1663-9812} Impact Factor= 5.988
  • "Expression patterns and therapeutic implications of CDK4 across multiple carcinomas: a molecular docking and MD simulation study" Medical Oncology, 39(10): DOI No. 10.1007/s12032-022-01779-9 {ISSN: 1559131X} Impact Factor= 3.738
  • "Expression Pattern and Prognostic Significance of Chemokines in Breast cancer: An Integrated Bioinformatics Analysis" Clinical Breast Cancer, 22(5): DOI No. 10.1016/j. clbc.2022.04.008 {ISSN: 1526-8209} Impact Factor= 3.225
  • "Cryptolepine Targets TOP2A and Inhibits Tumor Cell Proliferation in Breast Cancer Cells - An in vitro and in silico Study" Anti-Cancer Agents in Medicinal Chemistry, 22(3): DOI No. 10.2174/1871520622666220419135 {ISSN: 18755992} Impact Factor= 2.680
  • "Expression Pattern and Prognostic significance of CDKs in Breast Cancer: An Integrated Bioinformatic Study." Cancer Biomarkers, 34(3): DOI No. 10.3233/CBM-210186 {ISSN: 505-519} Impact Factor= 4.333
  • "Cyclin-Dependent Kinases in Breast Cancer: Expression Pattern and Therapeutic Implications" Medical Oncology, 34(6): DOI No. 10.1007/s12032-022-01731-x {ISSN: 1559131X} Impact Factor= 3.738
  • "antimicrobial properties of Delphinium cashmerianum L., a medicinal herb growing in Kashmir, India." Journal of Ethnopharmacology, 297(6): DOI No. 10.1016/j.jep.2022.115046 {ISSN: 0378-8741} Impact Factor= 5.107
  • "Natural therapeutics in aid of treating Alzheimer’s disease (AD): A green gateway towards ending the quest for treating neurological disorders" Frontiers in Neuroscience, 16(6): DOI No. 10.3389/fnins.2022.884345 {ISSN: 1662-453X} Impact Factor= 4.501
  • "Quinidine Drug Resistance transporter Knockout Candida cells modulate glucose transporter expression and accumulate metabolites leading to enhanced azole drug resistance" Fungal Genetics and Biology, 161(7): DOI No. 10.1016/j.fgb. {ISSN: 10871845} Impact Factor= 3.883
  • "Targeting Cyclin-dependent kinase 1 (CDK1) in Cancer: Molecular Docking and Dynamic Simulations of potential CDK1 Inhibitors" Medical Oncology, 39(4): DOI No. 10.1007/s {ISSN: 1559131X} Impact Factor= 3.738
  • "Strategies employed to evade the host immune response and the mechanism of drug resistance in Mycobacterium tuberculosis: In search of finding new targets" Current Pharmaceutical Biotechnology, 23(1): DOI No. 10.2174/1389201023666211222164 {ISSN: 1873-4316} Impact Factor= 2.840
  • "Evaluation of the In Vitro Antimicrobial Activities of Delphinium roylei: An Insight from Molecular Docking and MD-Simulation Studies" Medicinal Chemistry, 18(4): DOI No. 10.2174/1573406418666220429093 {ISSN: 1875-6638} Impact Factor= 2.329
  • "Manipulation and exploitation of host immune system by pathogenic Mycobacterium tuberculosis for its advantage" Future Microbiology, 17(8): DOI No. 10.2217/fmb-20 {ISSN: 1746-0913} Impact Factor= 3.553
  • "Natural products and their semi-synthetic derivatives against antimicrobial-resistant human pathogenic bacteria and fungi" Saudi Journal of Biological Sciences, 29(9): DOI No. 10.1016/j.sjbs {ISSN: 1319-562X} Impact Factor= 4.052
  • "Molecular docking analysis and evaluation of the antimicrobial properties of the constituents of Geranium wallichianum D. Don ex Sweet from Kashmir Himalaya" Scientific Reports (Springer-Nature), 12(7): DOI No. 10.1038/s41598-022-16102-9 {ISSN: 2045-2322} Impact Factor= 4.996
  • "Metabolite fingerprinting of phytoconstituents from Fritillaria cirrhosa D. Don and molecular docking analysis of bioactive peonidin with microbial drug target proteins." Scientific Reports (Nature Springer), 12(5): DOI No. 10.1038/s 4159 {ISSN: 245-2322} Impact Factor= 4.996
  • "Expression pattern and prognostic significance of baculoviral inhibitor of apoptosis repeat- containing 5 (BIRC5) in breast cancer: A comprehensive analysis." Advances in Cancer Biology-Metastasis, 4(3): DOI No. 10.1016/j. adc {ISSN: 2667-3940} Impact Factor= 0.0
  • "Metformin treatment ameliorates endocrine metabolic disturbances in the letrozole-induced PCOS mice model by modulating adiponectin Status" Obesity Medicine, 31(5): DOI No. 10.1016/j.obme {ISSN: 24518476} Impact Factor= 0.00
  • "A Novel Prognostic Biomarker with Potential of High Diagnostic Accuracy in Pulmonary Tuberculosis: An in silico Study" International Journal of Pharmaceutical Investigation, 12(2): DOI No. 10.5530/ijpi.2 {ISSN: 2230-9713} Impact Factor= 0.00

Books Published

  • "Introduction to Costimulation and Costimulatory Molecules". Elsevier Publishers USA. {ISBN: 978-0-12-80-2585-7} pp 44
  • "Concept of Reverse Costimulation and Its Role in Diseases". Elsevier Publishers USA. {ISBN: 978-0-12-80-2585-7} pp 37
  • "Costimulation Immunotherapy in Infectious Diseases". Elsevier Publishers USA. {ISBN: 978-0-12-80-2585-7} pp 45
  • "Costimulation Immunotherapy in Allergies and Asthma". Elsevier Publishers USA. {ISBN: 978-0-12-80-2585-7} pp 47
  • "Costimulation in Lymphomas and Cancers". Elsevier Publishers USA. {ISBN: 978-0-12-80-2585-7} pp 69
  • "T-Cell Costimulation and Its Applications in Diseases". Elsevier Publishers USA. {ISBN: 978-0-12-80-2585-7} pp 38
  • "Role of Natural Herbs in Stroke Prevention and Treatment". Nova Science Biomedical Publishers USA. {ISBN: 978-1-63483-555-8} pp 264
  • "An Introduction to Cerebrovascular Diseases". Nova Science Publishers New York USA. {ISBN: 978-1-63483-555-8} pp 51
  • "Immunobiology of Stroke". Nova Science Publishers New York USA. {ISBN: 978-1-63483-555-8} pp 61
  • "Natural Herbs, Human Brain and Neuroprotection". Nova Science Publishers New York USA. pp 62
  • "Natural Herbs in Stroke prevention and Treatment". Nova Science Publishers New York USA. pp 36
  • "Polyphenols from Natural Herbs in Neuroprotection". Nova Science Publishers New York USA. pp 47
  • "Role of Natural Herbs in Prevention and Treatment of Stroke". Nova Science Publishers New York USA. {ISBN: 978-1-63483-574-9} pp 310
  • "Basics and Fundamentals of Immunology". Nova Science Publishers USA. {ISBN: 978-1-53616-639-2} pp 334
  • "Immunoglobulins, Magic Bullets and Therapeutic Antibodies". Biomedical NOVA Science Publishers Newyork USA. {ISBN: 978-1-53616-903-4} pp 365
  • "Cytokines and their Therapeutic potential". Nova Science Publishers Newyork USA. {ISBN: 978-1-53617-017-7} pp 285
  • "The fundamentals of Hypersensitivities and Allergies". Nova Biomedical Science Publishers New York USA. {ISBN: 978-1-53617-012-2} pp 184
  • "Plant Metabolites in the Treatment of Cancer and cerebrovascular Diseases". OMICS Science International Publishers USA. {ISBN: 978-1-63278-073-7} pp 176
  • "Natural Medicine in Cerebrovascular Diseases". Ariana Publishers New Delhi India. {ISBN: 9789385497940} pp 127
  • "Nanomedicine in Human Health Therapeutics and Drug Delivery/Applications of Nanomaterials in Agriculture, Food Science, and Medicine". IGI Global Publishers. {ISBN: 9781799855644} pp 23
  • "Combination Therapies and their Effectiveness in Breast Cancer Treatment". NOVA Biomedical Science Publishers USA. {ISBN: 978-1-68507-195-0} pp 345
  • "Integrating Immunotherapy with Targeted Therapies and Chemotherapy: A New Paradigm in TNBC Treatment". Intech Open International Publishers UK. {ISBN: 978-1-83969-958-0} pp 46
  • "Role of immunogenetics polymorphisms in infectious diseases". Elsevier Publishers USA. {ISBN: 978-0-323-90053-9} pp 56
  • "Antioxidants (Natural and Synthetic) Screening Assays: An Overview". Bentham Science Publishers. {ISBN: 978-981-4998-88-8} pp 22
  • "Antioxidants in Cancer Prevention and Combination Therapy". Bentham Science Publishers. {ISBN: 978-981-4998-88-8} pp 18
  • "Immuno-onco-metabolism and Therapeutic Resistance". Springer Nature. {ISBN: 978-9811662256} pp 36
  • "Combinational Therapy in Triple Negative Breast Cancer". Elsevier Sciences USA. {ISBN: 9780323961363} pp 368
  • "Human Pathogenic Microbes: Diseases and Concerns". Elsevier Sciences USA. {ISBN: 9780323961271} pp 412
  • "Chapter 1 - Human pathogenic microbes (bacterial and fungal) and associated diseases". Elsevier. {ISBN: 978-0-323-96127-1} pp 30
  • "Chapter 2 - Evolution of antimicrobial drug resistance in human pathogenic bacteria". Elsevier. {ISBN: 978-0-323-96127-1} pp 22
  • "Chapter 3 - Evolution of antimicrobial drug resistance in human pathogenic fungi". Elsevier. {ISBN: 978-0-323-96127-1} pp 18
  • "Chapter 4 - Combating human bacterial infections: need for new antibacterial drugs and therapeutics". Elsevier. {ISBN: 978-0-323-96127-1} pp 31
  • "Chapter 5 - Combating human fungal infections: need for new antifungal drugs and therapies". Elsevier. {ISBN: 978-0-323-96127-1} pp 25
  • "Chapter 6 - Significance of immunotherapy for human bacterial diseases and antibacterial drug discovery". Elsevier. {ISBN: 978-0-323-96127-1} pp 32
  • "Chapter 7 - Significance of immunotherapy for human fungal diseases and antifungal drug discovery". Elsevier. {ISBN: 978-0-323-96127-1} pp 23
  • "Chapter 8 - Combinatorial approach to combat drug resistance in human pathogenic bacteria". Elsevier. {ISBN: 978-0-323-96127-1} pp 20
  • "Chapter 9 - Combinatorial approach to combat drug resistance in human pathogenic fungi". Elsevier. {ISBN: 978-0-323-96127-1} pp 16
  • "Chapter 10 - Recent trends in the development of bacterial and fungal vaccines". Elsevier. {ISBN: 978-0-323-96127-1} pp 27
  • "Human pathogenic microbes: diseases and concerns". Elsevier USA. {ISBN: 9780323961271} pp 432
  • "Combinational Therapy in Triple Negative Breast Cancer". Elsevier USA. {ISBN: 9780323961363} pp 386
  • "Role of tumor microenvironment in breast cancer and targeted Therapies". Elsevier USA. {ISBN: 9780443186967} pp 297

Research Projects Details:

Title of the ProjectFunding AgencyDatedAmount (in Rs.)
TNF receptor modulation and its impact on the cellular survival by natural herbs in oxygen glucose deprivation model of strokeSheikh Abdullah Bin Tuwaijri Chair for Applied Research in Stroke (SATCAS) Majmaah University KSA01-01-2015180,000.00
Neuroprotective effect of Elsholtzia densa and Artemisia amygdalina in cellular survival after Cerebral Ischemia in oxidative/inflammatory in vitro model of StrokeBHSR Centre Majmaah University25-03-20151,000,000.00
Elucidation of Molecular Mechanisms of Drug and Multidrug Resistance of MTB in Kashmir ValleySERB-DST GOI10-06-20191,850,000.00
Elucidation of Molecular Basis of Drug and Multidrug Tuberculosis Resistance of Mycobacterium tuberculosis in Kashmir ValleyScience and Engineering Research Board, Department of Science and Technology (SERB-DST) Govt of India11-09-20201,850,000.00
Targeting drug resistance cancer stem cells by combinational delivery of Quercetin/ Zerumbone in breast cancerJammu Kashmir Science Technology and Innovation Council Govt (JKDST&IC)27-10-20211,000,000.00
Elucidation of Molecular Basis of Drug and Multi-Drug Tuberculosis Resistance of mycobacterium tuberculosis in Kashmir ValleySCience and Engineering Research Board, Department of Science and Technology Govt of India (SERB-DST)10-06-20191,860,000.00

Research Scholars:

NameCourseStatusNature
Umar MehrajPh.D Awarded Whole Time
Bashir Ahmad SheikhPh.D Awarded Whole Time
Basharat Ahmad BhatPh.D Awarded Whole Time

Teaching:

DepartmentSubjectCourse TaughtSemester
Bio-ResourcesM. Sc BioresourcesAnimal Resource Regeneration2
Bio-ResourcesM. Sc BioresourcesBiological Interactions2
Bio-ResourcesM. Sc BioresourcesInfectious Diseases and Human Health2
Bio-ResourcesM. Sc BioresourcesHormones and Human Health3
Bio-ResourcesM. Sc BioresourcesInfectious Diseases and Livestock Health3
Bio-ResourcesM. Sc BioresourcesCellular andMolecular Immunology3
Bio-ResourcesM. Sc BioresourcesBiostatistics and Biotechniques3